Prevention and treatment of skin infections
Micronized silver sulfadiazine
Wide spectrum antimicrobial agent against gram (+) and gram (-) microorganisms, specially indicated against Pseudomona aeruginosa, Staphylococcus aureus, Proteus, Klebsiellas, Escherichia coli and Candida albicans.
MECHANISM OF ACTION:
Inclusion of Ag ion on the carboxyl link of the bacterias deoxyribonucleic acid with the following destruction of cellular membrane.
Inhibitor of bacterial para-aminobenzoic acid (PABA).
Maximimum active ingredient micronization enables a faster diffusion over the damaged tissue, with greater effectiveness, destroying microorganisms in less time.
Antibiotic soaked dressing
Antibiotic and corticosteroid soaked dressing
Antiseptic dressing on hydrosoluble base
Dermal lotion with
Essential Fatty Acids and Vitamin A
Hydrating and absorbing Gel
with Sodium Alginate and Calcium
with Zinc Oxyde and Vitamin A
Propóleo-D® line of pharmaceutical products has stabilized Propolis as its active ingredient and is comprised of two families of products defined by their delivery method oral or topical.
Topical use Propóleo-D®: dressings, cream, ointment, lotion, adhesive solution and powders.
Oral use Propóleo-D®: capsules and syrup.
Propolis pharmaceutical properties that support its therapeutic or prophylactic use are linked to its content of polyfenols: flavonoids, aromatic acids and esters; particularly caffeic acid phenethyl ester (CAPE)
It has antibacterial activity against Gram (+) and Gram (-) germs, including Staphylococcus aureus, Pseudomonas aeruginosa and Streptococcus hemolyticus, as well as antimycotic activity against Candida albicans and antiviral against Herpes and Poliovirus. Propolis mechanism of action against infections is multiple: antibacterial, by increasing permeability on bacterial membranes with loss of ions and nutrients, reducing germ viability; antipathogen inhibiting virulence and resistance factors of bacteria, like biofilm formation and production of enzymes related to with hosts tissue damage.
Topical Propolis promotes keratinocyte proliferation, stimulating granulation tissue formation and facilitating autolytic debridement, which speeds up epithelial reconstruction process and early wound closure.
Propolis has significant anti-inflammatory action by reducing production of several inflammatory mediators considered pathogenic factors of rheumatic diseases, arteriosclerosis and cancer; linked to its capability to inhibit kappa B nuclear transcription factor, master key to genetic regulation of immune inflammatory processes. Unlike synthetic antinflammatories which only reduce prostaglandin E2, it also reduces leukotrienes, proinflammatory cytokines and several enzymes responsible for generating oxygen reactive species (free radicals).
Propolis promotes a regulated immune system balance. Acts as immunological adjuvant, intensifying acquired immune response dependent on antigens and significantly reducing innate immune response mediators like interleukin 1-β, 6 and 8 and tumor necrosis factor α (proinflammatory cytokines). It also prevents degranulation of mast cells responsible for allergic reactions such as rhinitis and asthma.
Uruguayan Propolis antioxidant properties are very high due to its elevated content of polyphenols, inhibiting proinflammatory enzymes responsible for generating large quantities of oxygen reactive species during inflammatory process. This mechanism protects cell lipids and structural proteins from damage produced by oxygen stress.
Forms an homogeneous adherent film
Healing. Antimicrobial. Anti-inflammatory
For deep wet wounds
Hydrosoluble base formula
Enhances formation of scar tissue on wet wounds
For dry superficial lesions
Anti-inflammatory. Mucolyitic and cough suppressant
Terpropil® active ingredient is Nitrofurazone, synthetic chemical compound derivate from the nitrofurane nucleus.
Wide spectrum topical Antibacterial active against gram (+) and gram (-) bacteria
• Acts by altering the enzyme metabolism of bacterial cells even in the presence of blood, serum or pus.
• Effective over most germs responsible for superficial infections, even in those that developed antibiotic resistance.
• Prevents formation of scabs and keeps the affected area aseptic